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I’ve been on HRT for 6 months, with 5mg weekly injections for the last 3 of those months.
3 months ago, my E was 22 pg/ml, now it is 333 pg/ml.
Doctor says that is too high and is going to to reduce me to a “maintenance dose”. Just wanted to check with other people if this is consistent with their experiences. Thanks!

  • Tencho@lemmy.world
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    3 天前

    seems like you know a lot about this.

    I’m personally sitting somewhere in the 400-500pg/ml range as its where my energy is the highest. I’m doing monotherapy indefinitely.

    would you suggest i try to prioritize surgery so i can reduce my levels?

    Really im just curious what time frame a “temporary monotherapy” counts as.

    • dandelion (she/her)@lemmy.blahaj.zone
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      3 天前

      yes, I highly recommend an orchiectomy from a skillful surgeon, ideally someone that also performs vaginoplasties (so they are more likely to know how to preserve options for a future vaginoplasty if that becomes a possibility and desire later).

      The temporary timeline was at most a year, since in the U.S. insurance requires a minimum of 1 year on supervised HRT before allowing any trans gender-affirming surgeries.

      Anecdotally, I never found monotherapy as stable for my mood as having more normal estrogen levels post-op, but most of the stability just came from my body no longer occasionally producing testosterone levels I didn’t tolerate well. (High estrogen definitely made me more emotional, but in some ways I enjoyed how it felt - once my life calms down enough, I plan to incorporate occasionally more frequent or higher doses to simulate a monthly cycle.)